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KMID : 0366220090440040298
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Korean Journal of Hematology
2009 Volume.44 No. 4 p.298 ~ p.303
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Prolonged Extreme Thrombocytosis in a Postsplenectomy Patient with Hereditary Spherocytosis
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Park Yae-Min
Park Jin-Ny
Jo Yun-Jeong
Kim Sei-Hyun
Shin Kwen-Chul
Won In-Sik
Sym Sun-Jin
Cho Eun-Kyung
Shin Dong-Bok
Lee Jae-Hoon
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Abstract
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We report a case of prolonged extreme reactive thrombocytosis in a post-splenectomy patient with hereditary spherocytosis. A 29-year-old female patient presented with gall stones detected incidentally by abdominal ultrasonography. Her laboratory findings showed hemolytic anemia with spherocytosis on the peripheral blood smear and increased osmotic fragility. She was diagnosed with hereditary spherocytosis and underwent a laparoscopic cholecystectomy and splenectomy. After undergoing surgery, the hemolytic anemia was resolved but thrombocytosis was newly detected. Nineteen months after the splenectomy, the thrombocytosis was still persistent and extremely high. To our knowledge, this is the first report of a prolonged extreme reactive thrombocytosis after a splenectomy in Korea. (Korean J Hematol 2009;44:298-303.)
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KEYWORD
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Reactive thrombocytosis, Postsplenectomy, Hereditary spherocytosis
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